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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1J
All Species:
20.61
Human Site:
S227
Identified Species:
41.21
UniProt:
Q5JR12
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5JR12
NP_005158.5
505
54834
S227
W
S
S
Q
K
E
V
S
H
E
S
L
V
V
G
Chimpanzee
Pan troglodytes
XP_513628
505
54871
T227
W
S
S
Q
K
E
V
T
H
E
S
L
V
V
G
Rhesus Macaque
Macaca mulatta
XP_001096598
450
48605
H212
P
D
S
S
D
P
S
H
L
L
G
P
Q
S
C
Dog
Lupus familis
XP_540335
509
54913
T231
W
S
S
Q
K
E
V
T
H
E
S
L
V
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q149T7
507
55531
T228
W
S
P
Q
K
E
V
T
H
D
S
L
I
V
G
Rat
Rattus norvegicus
Q641Y6
504
55192
H226
S
P
Q
K
E
V
T
H
D
S
L
V
V
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507685
606
67811
V219
G
G
C
C
A
L
V
V
V
Y
L
L
G
K
L
Chicken
Gallus gallus
XP_418000
495
54949
S217
F
H
L
E
K
A
V
S
H
E
S
L
V
I
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q05AL2
516
56543
D252
E
N
A
F
K
E
M
D
A
H
I
A
R
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608468
651
72868
I223
F
F
N
M
D
S
L
I
A
Q
D
C
D
R
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798783
601
66691
S306
P
F
N
E
K
E
V
S
V
E
S
L
V
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P49598
399
43332
V161
R
E
R
L
H
D
I
V
K
K
E
V
E
V
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
85.5
93.1
N.A.
88.3
88.3
N.A.
56.1
68.5
N.A.
47.2
N.A.
30.8
N.A.
N.A.
36.1
Protein Similarity:
100
100
86.7
96.2
N.A.
91.3
90.6
N.A.
63.2
77
N.A.
62
N.A.
45
N.A.
N.A.
51.2
P-Site Identity:
100
93.3
6.6
93.3
N.A.
73.3
6.6
N.A.
13.3
60
N.A.
13.3
N.A.
0
N.A.
N.A.
66.6
P-Site Similarity:
100
100
6.6
100
N.A.
93.3
26.6
N.A.
13.3
80
N.A.
33.3
N.A.
26.6
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
9
0
0
17
0
0
9
0
0
9
% A
% Cys:
0
0
9
9
0
0
0
0
0
0
0
9
0
0
9
% C
% Asp:
0
9
0
0
17
9
0
9
9
9
9
0
9
0
0
% D
% Glu:
9
9
0
17
9
50
0
0
0
42
9
0
9
9
0
% E
% Phe:
17
17
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
0
0
0
0
0
0
9
0
9
9
50
% G
% His:
0
9
0
0
9
0
0
17
42
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
9
0
0
9
0
9
9
0
% I
% Lys:
0
0
0
9
59
0
0
0
9
9
0
0
0
9
0
% K
% Leu:
0
0
9
9
0
9
9
0
9
9
17
59
0
0
9
% L
% Met:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
9
% M
% Asn:
0
9
17
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
17
9
9
0
0
9
0
0
0
0
0
9
0
0
0
% P
% Gln:
0
0
9
34
0
0
0
0
0
9
0
0
9
0
0
% Q
% Arg:
9
0
9
0
0
0
0
0
0
0
0
0
9
9
9
% R
% Ser:
9
34
34
9
0
9
9
25
0
9
50
0
0
9
0
% S
% Thr:
0
0
0
0
0
0
9
25
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
59
17
17
0
0
17
50
50
0
% V
% Trp:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _